Anti-Ferritin Heavy Chain Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | P02794 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Ferritin Heavy Chain Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
Gene ID | 2495 |
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Other Names | Ferritin heavy chain, Ferritin H subunit, 1.16.3.1, Cell proliferation-inducing gene 15 protein, Ferritin heavy chain, N-terminally processed, FTH1, FTH, FTHL6 |
Calculated MW | 21226 Da |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 17F96 |
Immunogen | A synthesized peptide derived from human Ferritin Heavy Chain |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | FTH1 |
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Synonyms | FTH, FTHL6 |
Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293). |
Cellular Location | Cytoplasm. Lysosome. Cytoplasmic vesicle, autophagosome |
Tissue Location | Expressed in the liver. |
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