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> home > Products > Primary Antibodies > Antibody Collections > Liver positive > Anti-Fibulin 5 Rabbit Monoclonal Antibody
Anti-Fibulin 5 Rabbit Monoclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q9UBX5 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Fibulin 5 Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse. |
| Gene ID | 10516 |
|---|---|
| Other Names | Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50, FBLN5, DANCE |
| Calculated MW | 50180 Da |
| Application Details | WB 1:500-1:2000 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 17F39 |
| Immunogen | A synthesized peptide derived from human Fibulin 5 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | FBLN5 |
|---|---|
| Synonyms | DANCE |
| Function | Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108). |
| Cellular Location | Secreted. Secreted, extracellular space, extracellular matrix. Note=co-localizes with ELN in elastic fibers. |
| Tissue Location | Expressed in skin fibroblasts (at protein level) (PubMed:17035250). Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823). |
Research Areas
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Application Protocols
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$ 370.00
Cat# ABO15163
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