Anti-SLC2A1 Antibody Picoband™ (monoclonal, 10C10)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, IF, ICC, FC |
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Primary Accession | P11166 |
Host | Mouse |
Isotype | Mouse IgG1 |
Reactivity | Human |
Clonality | Monoclonal |
Format | Lyophilized |
Description | Anti-SLC2A1 Antibody Picoband™ (monoclonal, 10C10) . Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. |
Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500 µg/ml. |
Gene ID | 6513 |
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Other Names | Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1 (HGNC:11005) |
Calculated MW | 55 kDa |
Application Details | Western blot, 0.1-0.5 µg/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1 µg/ml Immunocytochemistry/Immunofluorescence, 5 µg/ml Flow Cytometry, 1-3 µg/1x10^6 cells |
Subcellular Localization | Cell membrane. Multi-pass membrane protein. Melanosome. |
Tissue Specificity | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. |
Contents | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Clone Names | Clone: 10C10 |
Immunogen | E.coli-derived human SLC2A1 recombinant protein (Position: R92-V492). Human SLC2A1 shares 98% and 98.3% amino acid (aa) sequence identity with mouse and rat SLC2A1, respectively. |
Cross Reactivity | No cross-reactivity with other proteins. |
Storage | Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Name | SLC2A1 (HGNC:11005) |
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Function | Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:10227690, PubMed:10954735, PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:32860739). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed:18245775, PubMed:19449892). Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy- independent, facilitative transport of glucose into the brain (PubMed:10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity). Required for mesendoderm differentiation (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Melanosome. Photoreceptor inner segment {ECO:0000250|UniProtKB:P17809}. Note=Localizes primarily at the cell surface (PubMed:18245775, PubMed:19449892, PubMed:23219802, PubMed:24847886, PubMed:25982116). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) |
Tissue Location | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues |

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