Anti-CRX Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
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Primary Accession | O43186 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-CRX Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
Gene ID | 1406 |
---|---|
Other Names | Cone-rod homeobox protein, CRX, CORD2 |
Calculated MW | 32261 Da |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: AFIO-3 |
Immunogen | A synthesized peptide derived from human CRX Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | CRX |
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Synonyms | CORD2 |
Function | Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
Tissue Location | Retina. |

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