Anti-alpha 1 Antichymotrypsin SERPINA3 Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC, IP |
---|---|
Primary Accession | P01011 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-alpha 1 Antichymotrypsin SERPINA3 Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human. |
Gene ID | 12 |
---|---|
Other Names | Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT |
Calculated MW | 47651 Da |
Application Details | WB 1:500-1:1000 IHC 1:100-1:500 ICC/IF 1:50-1:200 IP 1:30 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: ADED-19 |
Immunogen | A synthesized peptide derived from human alpha 1 Antichymotrypsin Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | SERPINA3 |
---|---|
Synonyms | AACT |
Function | Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
Cellular Location | Secreted. |
Tissue Location | Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. |
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