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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-beta 2 Adrenergic Receptor ADRB2 Rabbit Monoclonal Antibody
Anti-beta 2 Adrenergic Receptor ADRB2 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IP |
|---|---|
| Primary Accession | P07550 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-beta 2 Adrenergic Receptor ADRB2 Rabbit Monoclonal Antibody . Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 154 |
|---|---|
| Other Names | Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR |
| Calculated MW | 46459 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 IP 1:30 |
| Subcellular Localization | Cell membrane ; Multi-pass membrane protein. Colocalizes with VHL at the cell membrane. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AE-1 |
| Immunogen | A synthesized peptide derived from human beta 2 Adrenergic Receptor |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | ADRB2 |
|---|---|
| Synonyms | ADRB2R, B2AR |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) Activated receptors are also detected within the Golgi apparatus (PubMed:27481942). |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO14312
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