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> home > Products > Primary Antibodies > Stem Cells > Anti-14-3-3 alpha + beta YWHAB Rabbit Monoclonal Antibody
Anti-14-3-3 alpha + beta YWHAB Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IF, ICC, IP, FC |
|---|---|
| Primary Accession | P31946 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-14-3-3 alpha + beta YWHAB Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 7529 |
|---|---|
| Other Names | 14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein beta/alpha, N-terminally processed, YWHAB |
| Calculated MW | 28082 MW KDa |
| Application Details | WB 1:500-1:1000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:30 FC 1:30 |
| Subcellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: HHA-25 |
| Immunogen | A synthesized peptide derived from human 14-3-3 alpha + beta |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | YWHAB |
|---|---|
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13. |
| Cellular Location | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
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Application Protocols
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$ 370.00
Cat# ABO14266
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