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> home > Products > Primary Antibodies > Signal Transduction > Anti-Heme Oxygenase 1 HMOX1 Rabbit Monoclonal Antibody
Anti-Heme Oxygenase 1 HMOX1 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IP, FC |
|---|---|
| Primary Accession | P09601 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Heme Oxygenase 1 HMOX1 Rabbit Monoclonal Antibody . Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse. |
| Gene ID | 3162 |
|---|---|
| Other Names | Heme oxygenase 1, HO-1, 1.14.14.18, Heme oxygenase 1 soluble form, HMOX1, HO, HO1 |
| Calculated MW | 32819 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 IP 1:50 FC 1:50 |
| Subcellular Localization | Microsome. Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side. |
| Tissue Specificity | Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level).. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AEG-8 |
| Immunogen | A synthesized peptide derived from human Heme Oxygenase 1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | HMOX1 |
|---|---|
| Synonyms | HO, HO1 |
| Function | [Heme oxygenase 1]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron (PubMed:11121422, PubMed:19556236, PubMed:7703255). Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis (PubMed:20055707). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side |
| Tissue Location | Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level) |
Research Areas
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Application Protocols
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$ 370.00
Cat# ABO14222
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