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> home > Products > Primary Antibodies > Signal Transduction > Anti-Laminin beta 1 LAMB1 Rabbit Monoclonal Antibody
Anti-Laminin beta 1 LAMB1 Rabbit Monoclonal Antibody
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Application 
| WB, FC |
|---|---|
| Primary Accession | P07942 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Laminin beta 1 LAMB1 Rabbit Monoclonal Antibody . Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 3912 |
|---|---|
| Other Names | Laminin subunit beta-1, Laminin B1 chain, Laminin-1 subunit beta, Laminin-10 subunit beta, Laminin-12 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-8 subunit beta, LAMB1 |
| Calculated MW | 198038 MW KDa |
| Application Details | WB 1:500-1:2000 FC 1:50 |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane. Major component. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AODF-12 |
| Immunogen | A synthesized peptide derived from human Laminin beta 1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | LAMB1 |
|---|---|
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. |
| Cellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO14196
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