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> home > Products > Primary Antibodies > Stem Cells > Anti-CEA (CD66e) CEACAM5 Rabbit Monoclonal Antibody
Anti-CEA (CD66e) CEACAM5 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IF, ICC |
|---|---|
| Primary Accession | P06731 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-CEA (CD66e) CEACAM5 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human. |
| Gene ID | 1048 |
|---|---|
| Other Names | Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5, CEA |
| Calculated MW | 76795 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 |
| Subcellular Localization | Cell membrane ; Lipid-anchor, GPI-anchor. |
| Tissue Specificity | Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AAOA-3 |
| Immunogen | A synthesized peptide derived from human CEA (CD66e) |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | CEACAM5 |
|---|---|
| Synonyms | CEA |
| Function | Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:10864933, PubMed:10910050, PubMed:2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface Note=Localized to the apical glycocalyx surface |
| Tissue Location | Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. |
Research Areas
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Application Protocols
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$ 370.00
Cat# ABO14100
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