Anti-Flotillin 2 FLOT2 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
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Primary Accession | Q14254 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Flotillin 2 FLOT2 Rabbit Monoclonal Antibody . Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 2319 |
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Other Names | Flotillin-2, Epidermal surface antigen, ESA, Membrane component chromosome 17 surface marker 1, FLOT2, ESA1, M17S1 |
Calculated MW | 47064 MW KDa |
Application Details | WB 1:500-1:2000 IP 1:30 |
Subcellular Localization | Cell membrane ; Peripheral membrane protein. Membrane, caveola ; Peripheral membrane protein. Endosome. Membrane-associated protein of caveolae. |
Tissue Specificity | In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: GB-6 |
Immunogen | A synthesized peptide derived from human Flotillin 2 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | FLOT2 |
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Synonyms | ESA1, M17S1 |
Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function. |
Cellular Location | Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome Membrane; Lipid-anchor. Note=Membrane- associated protein of caveolae |
Tissue Location | In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes |
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