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> home > Products > Primary Antibodies > Signal Transduction > Anti-Caveolin-3 CAV3 Rabbit Monoclonal Antibody
Anti-Caveolin-3 CAV3 Rabbit Monoclonal Antibody
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Application 
| WB, IP |
|---|---|
| Primary Accession | P56539 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Caveolin-3 CAV3 Rabbit Monoclonal Antibody . Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 859 |
|---|---|
| Other Names | Caveolin-3, M-caveolin, CAV3 |
| Calculated MW | 17259 MW KDa |
| Application Details | WB 1:500-1:2000 IP 1:50 |
| Subcellular Localization | Golgi apparatus membrane ; Peripheral membrane protein. Cell membrane ; Peripheral membrane protein. Membrane, caveola ; Peripheral membrane protein. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).. |
| Tissue Specificity | Expressed predominantly in muscle.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: FE-3 |
| Immunogen | A synthesized peptide derived from human Caveolin-3 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | CAV3 |
|---|---|
| Function | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564). |
| Cellular Location | Golgi apparatus membrane; Peripheral membrane protein. Cell membrane {ECO:0000250|UniProtKB:P51638}; Peripheral membrane protein. Membrane, caveola {ECO:0000250|UniProtKB:P51637}; Peripheral membrane protein. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P51637}. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity) |
| Tissue Location | Expressed predominantly in muscle. |
Research Areas
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Application Protocols
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$ 370.00
Cat# ABO14016
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