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> home > Products > Primary Antibodies > Signal Transduction > Anti-Myoglobin MB Rabbit Monoclonal Antibody
Anti-Myoglobin MB Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IF, ICC, IP |
|---|---|
| Primary Accession | P02144 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Myoglobin MB Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 4151 |
|---|---|
| Other Names | Myoglobin, Nitrite reductase MB, 1.7.-.-, Pseudoperoxidase MB, 1.11.1.-, MB (HGNC:6915) |
| Calculated MW | 17184 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:30 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: FOD-13 |
| Immunogen | A synthesized peptide derived from human Myoglobin |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | MB (HGNC:6915) |
|---|---|
| Function | Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand (PubMed:30918256, PubMed:34679218). Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide (PubMed:32891753). Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity (PubMed:34679218). |
| Cellular Location | Cytoplasm, sarcoplasm |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13980
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