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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-mGluR1 GRM1 Rabbit Monoclonal Antibody
Anti-mGluR1 GRM1 Rabbit Monoclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q13255 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-mGluR1 GRM1 Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 2911 |
|---|---|
| Other Names | Metabotropic glutamate receptor 1, mGluR1, GRM1, GPRC1A, MGLUR1 |
| Calculated MW | 132357 MW KDa |
| Application Details | WB 1:500-1:2000 |
| Subcellular Localization | Cell membrane ; Multi-pass membrane protein. |
| Tissue Specificity | Detected in brain. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: IGI-7 |
| Immunogen | A synthesized peptide derived from human mGluR1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | GRM1 |
|---|---|
| Synonyms | GPRC1A, MGLUR1 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum (PubMed:24603153, PubMed:28886343, PubMed:7476890). May function in the light response in the retina (By similarity). Induces GRID1 and GRID2 cation-channel activation via GNAQ-PLC-PKC pathway in dopaminergic neurons and cerebellar Purkinje cell, respectively (PubMed:24357660, PubMed:27276689). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein |
| Tissue Location | Detected in brain.. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13860
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