Anti-STAT5b Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC, IP |
---|---|
Primary Accession | P51692 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-STAT5b Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 6777 |
---|---|
Other Names | Signal transducer and activator of transcription 5B, STAT5B |
Calculated MW | 89866 MW KDa |
Application Details | WB 1:1000-1:2000 IHC 1:1000-1:2000 ICC/IF 1:1000-1:2000 IP 1:40 |
Subcellular Localization | Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: HDF-19 |
Immunogen | A synthesized peptide derived from human STAT5b |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | STAT5B |
---|---|
Function | Carries out a dual function: signal transduction and activation of transcription (PubMed:29844444). Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. |
Cellular Location | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation. |
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