Anti-Nestin Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC, IF, ICC |
---|---|
Primary Accession | P48681 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Nestin Rabbit Monoclonal Antibody . Tested in IHC, ICC/IF applications. This antibody reacts with Human, Rat. |
Gene ID | 10763 |
---|---|
Other Names | Nestin, NES |
Calculated MW | 177439 MW KDa |
Application Details | IHC 1:50-1:200 ICC/IF 1:50-1:200 |
Tissue Specificity | CNS stem cells. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: FBH-14 |
Immunogen | A synthesized peptide derived from human Nestin |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | NES |
---|---|
Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen- stimulated proliferation of neural progenitor cells (By similarity). |
Tissue Location | CNS stem cells. |
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