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> home > Products > Primary Antibodies > Signal Transduction > Anti-TIMP1 Rabbit Monoclonal Antibody
Anti-TIMP1 Rabbit Monoclonal Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | P01033 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-TIMP1 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
| Gene ID | 7076 |
|---|---|
| Other Names | Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP |
| Calculated MW | 23171 MW KDa |
| Application Details | WB 1:500-1:1000 IHC 1:50-1:200 |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Detected in rheumatoid synovial fluid (at protein level).. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AOOI-20 |
| Immunogen | A synthesized peptide derived from human TIMP1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | TIMP1 |
|---|---|
| Synonyms | CLGI, TIMP |
| Function | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. |
| Cellular Location | Secreted |
| Tissue Location | Detected in rheumatoid synovial fluid (at protein level). |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13730
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