Anti-Hsp20 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC |
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Primary Accession | O14558 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Hsp20 Rabbit Monoclonal Antibody . Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 126393 |
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Other Names | Heat shock protein beta-6, HspB6, Heat shock 20 kDa-like protein p20, Heat shock protein family B member 6, HSPB6 |
Calculated MW | 17136 MW KDa |
Application Details | WB 1:5000-1:10000 IHC 1:50-1:200 FC 1:50 |
Subcellular Localization | Cytoplasm. Nucleus. Translocates to nuclear foci during heat shock. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: IAD-8 |
Immunogen | A synthesized peptide derived from human Hsp20 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | HSPB6 |
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Function | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity. |
Cellular Location | Cytoplasm. Nucleus. Secreted Note=Translocates to nuclear foci during heat shock |
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