Anti-CDC45/Cdc45L Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, IF, ICC, FC |
---|---|
Primary Accession | O75419 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-CDC45/Cdc45L Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 8318 |
---|---|
Other Names | Cell division control protein 45 homolog, PORC-PI-1, CDC45 (HGNC:1739), CDC45L, CDC45L2 |
Calculated MW | 65569 MW KDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 FC 1:50 |
Subcellular Localization | Cytoplasm. Nucleus. |
Tissue Specificity | Widely expressed, highest levels are found in adult testis and thymus and in fetal liver. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: AD-3 |
Immunogen | A synthesized peptide derived from human CDC45 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | CDC45 (HGNC:1739) |
---|---|
Synonyms | CDC45L, CDC45L2 |
Function | Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. |
Cellular Location | Nucleus. Chromosome. Note=Associates with chromatin |
Tissue Location | Widely expressed, highest levels are found in adult testis and thymus and in fetal liver |

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