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Anti-SOX10 Rabbit Monoclonal Antibody
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- BACKGROUND
Application 
| IHC |
|---|---|
| Primary Accession | P56693 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-SOX10 Rabbit Monoclonal Antibody . Tested in IHC application. This antibody reacts with Human. |
| Gene ID | 6663 |
|---|---|
| Other Names | Transcription factor SOX-10, SOX10 |
| Calculated MW | 49911 MW KDa |
| Application Details | IHC 1:50-1:200 |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Expressed in fetal brain and in adult brain, heart, small intestine and colon. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: GIE-19 |
| Immunogen | A synthesized peptide derived from human SOX10 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | SOX10 |
|---|---|
| Function | Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250|UniProtKB:Q04888} |
| Tissue Location | Expressed in fetal brain and in adult brain, heart, small intestine and colon |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13687
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