Anti-IL1RA Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC, IP, FC |
---|---|
Primary Accession | P18510 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-IL1RA Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 3557 |
---|---|
Other Names | Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA |
Calculated MW | 20055 MW KDa |
Application Details | WB 1:5000-1:20000 IHC 1:50-1:200 ICC/IF 1:50-1:200 FC 1:50 IP 1:50 |
Subcellular Localization | Isoform 1: Secreted. |
Tissue Specificity | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: GEI-9 |
Immunogen | A synthesized peptide derived from human IL1RA |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | IL1RN |
---|---|
Synonyms | IL1F3, IL1RA |
Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
Cellular Location | [Isoform 1]: Secreted [Isoform 3]: Cytoplasm. |
Tissue Location | The intracellular form of IL1RN is predominantly expressed in epithelial cells |
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