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> home > Products > Primary Antibodies > Signal Transduction > Anti-MUC16/Ca125 Rabbit Monoclonal Antibody
Anti-MUC16/Ca125 Rabbit Monoclonal Antibody
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Application 
| WB, IF, ICC, FC |
|---|---|
| Primary Accession | Q8WXI7 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-MUC16/Ca125 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human. |
| Gene ID | 94025 |
|---|---|
| Other Names | Mucin-16, MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125, MUC16 (HGNC:15582) |
| Calculated MW | 1519175 MW KDa |
| Application Details | WB 1:5000-1:20000 ICC/IF 1:50-1:200 FC 1:100 |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain. |
| Tissue Specificity | Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: GOG-13 |
| Immunogen | A synthesized peptide derived from human MUC16 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | MUC16 (HGNC:15582) |
|---|---|
| Function | Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain |
| Tissue Location | Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas |
Research Areas
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$ 370.00
Cat# ABO13674
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