Anti-MEKK2 MAP3K2 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, IF, ICC, IP, FC |
---|---|
Primary Accession | Q9Y2U5 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-MEKK2 MAP3K2 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 10746 |
---|---|
Other Names | Mitogen-activated protein kinase kinase kinase 2, 2.7.11.25, MAPK/ERK kinase kinase 2, MEK kinase 2, MEKK 2, MAP3K2, MAPKKK2, MEKK2 |
Calculated MW | 69741 MW KDa |
Application Details | WB 1:5000-1:20000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:30 FC 1:50 |
Subcellular Localization | Cytoplasm. Nucleus. Upon EGF stimulation, translocates into the nucleus. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: FHC-13 |
Immunogen | A synthesized peptide derived from human MEKK2 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | MAP3K2 |
---|---|
Synonyms | MAPKKK2, MEKK2 |
Function | Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and- run dynamics. |
Cellular Location | Cytoplasm. Nucleus. Note=Upon EGF stimulation, translocates into the nucleus |

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