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> home > Products > Primary Antibodies > Signal Transduction > Anti-WASF2 Rabbit Monoclonal Antibody
Anti-WASF2 Rabbit Monoclonal Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9Y6W5 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-WASF2 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 10163 |
|---|---|
| Other Names | Actin-binding protein WASF2, Protein WAVE-2, Verprolin homology domain-containing protein 2, Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, WASF2 (HGNC:12733) |
| Calculated MW | 54284 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell projection, lamellipodium. At the interface between the lamellipodial actin meshwork and the membrane.. |
| Tissue Specificity | Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: FFG-23 |
| Immunogen | A synthesized peptide derived from human WASF2 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | WASF2 (HGNC:12733) |
|---|---|
| Function | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Basolateral cell membrane. Note=At the interface between the lamellipodial actin meshwork and the membrane. |
| Tissue Location | Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13667
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