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Anti-SDHB Rabbit Monoclonal Antibody
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- BACKGROUND
Application 
| WB, IHC, IP, FC |
|---|---|
| Primary Accession | P21912 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-SDHB Rabbit Monoclonal Antibody . Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 6390 |
|---|---|
| Other Names | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, 1.3.5.1, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1 |
| Calculated MW | 31630 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 IP 1:50 FC 1:50 |
| Subcellular Localization | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: ABDF-19 |
| Immunogen | A synthesized peptide derived from human SDHB |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | SDHB |
|---|---|
| Synonyms | SDH, SDH1 |
| Function | Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:26925370, PubMed:27604842). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol- oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13558
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