Anti-SDHB Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, IP, FC |
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Primary Accession | P21912 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-SDHB Rabbit Monoclonal Antibody . Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 6390 |
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Other Names | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, 1.3.5.1, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1 |
Calculated MW | 31630 MW KDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 IP 1:50 FC 1:50 |
Subcellular Localization | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: ABDF-19 |
Immunogen | A synthesized peptide derived from human SDHB |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | SDHB |
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Synonyms | SDH, SDH1 |
Function | Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:26925370, PubMed:27604842). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol- oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). |
Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |

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