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> home > Products > Primary Antibodies > Antibody Collections > Skin Melanoma positive > Anti-SDHA Rabbit Monoclonal Antibody
Anti-SDHA Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IF, ICC, IP, FC |
|---|---|
| Primary Accession | P31040 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-SDHA Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 6389 |
|---|---|
| Other Names | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, 1.3.5.1, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF |
| Calculated MW | 72692 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:20 FC 1:20 |
| Subcellular Localization | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AADA-19 |
| Immunogen | A synthesized peptide derived from human SDHA |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | SDHA |
|---|---|
| Synonyms | SDH2, SDHF |
| Function | Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:10746566, PubMed:24781757). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol- oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). Can act as a tumor suppressor (PubMed:20484225). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13531
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