Anti-FASN/Fatty Acid Synthase Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC, IP, FC |
---|---|
Primary Accession | P49327 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-FASN/Fatty Acid Synthase Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 2194 |
---|---|
Other Names | Fatty acid synthase, 2.3.1.85, Type I fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, 2.3.1.38, [Acyl-carrier-protein] S-malonyltransferase, 2.3.1.39, 3-oxoacyl-[acyl-carrier-protein] synthase, 2.3.1.41, 3-oxoacyl-[acyl-carrier-protein] reductase, 1.1.1.100, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 4.2.1.59, Enoyl-[acyl-carrier-protein] reductase, 1.3.1.39, Acyl-[acyl-carrier-protein] hydrolase, 3.1.2.14, FASN, FAS |
Calculated MW | 273427 MW KDa |
Application Details | WB 1:1000-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 FC 1:50 |
Subcellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Ubiquitous. Prominent expression in brain, lung, and liver.. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: IIA-6 |
Immunogen | A synthesized peptide derived from human FASN |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | FASN |
---|---|
Synonyms | FAS |
Function | Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. |
Cellular Location | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
Tissue Location | Ubiquitous. Prominent expression in brain, lung, liver and mammary gland. |
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