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Anti-PAX6 Rabbit Monoclonal Antibody

     
  •  - Anti-PAX6 Rabbit Monoclonal Antibody ABO13470
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
    detail
  •  - Anti-PAX6 Rabbit Monoclonal Antibody ABO13470
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
    detail
  •  - Anti-PAX6 Rabbit Monoclonal Antibody ABO13470
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
    detail
  •  - Anti-PAX6 Rabbit Monoclonal Antibody ABO13470
    Western blot analysis of PAX6 expression in HeLa cell lysate.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC
Primary Accession P26367
Host Rabbit
Isotype Rabbit IgG
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Format Liquid
Description Anti-PAX6 Rabbit Monoclonal Antibody . Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Additional Information
Gene ID 5080
Other Names Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Calculated MW 46683 MW KDa
Application Details WB 1:1000-1:2000
IHC 1:50-1:200
FC 1:500
Subcellular Localization Nucleus.
Tissue Specificity Fetal eye, brain, spinal cord and olfactory epithelium. Isoform 5a is less abundant than the PAX6 shorter form.
Contents Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names Clone: HEB-16
Immunogen A synthesized peptide derived from human PAX6
Purification Affinity-chromatography
Storage Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Information
Name PAX6
Synonyms AN2
Function Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1- mediated gene expression (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016}
Tissue Location [Isoform 1]: Expressed in lymphoblasts.
Research Areas
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$ 370.00
Cat# ABO13470
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