Anti-CCR3 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC |
---|---|
Primary Accession | P51677 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-CCR3 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 1232 |
---|---|
Other Names | C-C chemokine receptor type 3, C C CKR3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR 3, CKR3, Eosinophil eotaxin receptor, CD193, CCR3, CMKBR3 |
Calculated MW | 41044 MW KDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: ECE-3 |
Immunogen | A synthesized peptide derived from human CCR3 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | CCR3 |
---|---|
Synonyms | CMKBR3 |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | In eosinophils as well as trace amounts in neutrophils and monocytes. |
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