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> home > Products > Primary Antibodies > Signal Transduction > Anti-Rab4 RAB4A Rabbit Monoclonal Antibody
Anti-Rab4 RAB4A Rabbit Monoclonal Antibody
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Application 
| WB, IF, ICC, FC |
|---|---|
| Primary Accession | P20338 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Rab4 RAB4A Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 5867 |
|---|---|
| Other Names | Ras-related protein Rab-4A, 3.6.5.2, RAB4A, RAB4 |
| Calculated MW | 24390 MW KDa |
| Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 FC 1:50 |
| Subcellular Localization | Membrane; Peripheral membrane protein. Cytoplasm. Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: CCI-18 |
| Immunogen | A synthesized peptide derived from human Rab4 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | RAB4A |
|---|---|
| Synonyms | RAB4 |
| Function | Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420). Involved in protein transport (PubMed:29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100). Acts as a regulator of platelet alpha- granule release during activation and aggregation of platelets (By similarity). |
| Cellular Location | Membrane; Peripheral membrane protein. Cytoplasm Early endosome membrane {ECO:0000250|UniProtKB:P05714}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05714}. Recycling endosome membrane {ECO:0000250|UniProtKB:P05714}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05714}. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1 |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13352
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