Anti-LOX Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC, IP, FC |
---|---|
Primary Accession | P28300 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-LOX Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 4015 |
---|---|
Other Names | Protein-lysine 6-oxidase, 1.4.3.13, Lysyl oxidase, Protein-lysine 6-oxidase, long form, Protein-lysine 6-oxidase, short form, LOX |
Calculated MW | 46944 MW KDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 FC 1:60 |
Subcellular Localization | Secreted, extracellular space. |
Tissue Specificity | Heart, placenta, skeletal muscle, kidney, lung and pancreas.. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: ABEO-12 |
Immunogen | A synthesized peptide derived from human LOX |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | LOX |
---|---|
Function | Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:26838787). Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity). |
Cellular Location | Secreted. Secreted, extracellular space |
Tissue Location | Heart, placenta, skeletal muscle, kidney, lung and pancreas. |
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