Anti-VWF/Von Willebrand Factor Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P04275 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-VWF/Von Willebrand Factor Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
Gene ID | 7450 |
---|---|
Other Names | von Willebrand factor, vWF, von Willebrand antigen 2, von Willebrand antigen II, VWF, F8VWF |
Calculated MW | 309265 MW KDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
Subcellular Localization | Secreted. Secreted, extracellular space, extracellular matrix. Localized to storage granules. |
Tissue Specificity | Plasma. |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: IHF-22 |
Immunogen | A synthesized peptide derived from human VWF |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | VWF |
---|---|
Synonyms | F8VWF |
Function | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
Cellular Location | Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules |
Tissue Location | Plasma. |
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