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> home > Products > Primary Antibodies > Antibody Collections > Mitochondrion > Anti-SDHA Picoband Antibody
Anti-SDHA Picoband Antibody
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Application 
| WB |
|---|---|
| Primary Accession | P31040 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 6389 |
|---|---|
| Other Names | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, 1.3.5.1, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF |
| Calculated MW | 72692 MW KDa |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Mouse, Rat |
| Subcellular Localization | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| Protein Name | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Immunogen | E.coli-derived human SDHA recombinant protein (Position: S44-L380). Human SDHA shares 98.2% and 97.6% amino acid (aa) sequence identity with mouse and rat SDHA, respectively. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. |
| Name | SDHA |
|---|---|
| Synonyms | SDH2, SDHF |
| Function | Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:10746566, PubMed:24781757). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol- oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). Can act as a tumor suppressor (PubMed:20484225). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
Research Areas
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$ 370.00
Cat# ABO12123
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