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Anti-MASPIN Picoband Antibody

     
  • WB - Anti-MASPIN Picoband Antibody ABO12047
    Anti- MASPIN Picoband antibody, ABO12047, Western blottingAll lanes: Anti MASPIN (ABO12047) at 0.5ug/mlLane 1: Mouse Intestine Tissue Lysate at 50ugLane 2: Human Placenta Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugLane 4: MM231 Whole Cell Lysate at 40ugPredicted bind size: 42KDObserved bind size: 42KD
    detail
  • IHC - Anti-MASPIN Picoband Antibody ABO12047
    Anti- MASPIN Picoband antibody, ABO12047, IHC(P)IHC(P): Mouse Intestine Tissue
    detail
  • IHC - Anti-MASPIN Picoband Antibody ABO12047
    Anti- MASPIN Picoband antibody, ABO12047, IHC(P)IHC(P): Rat Intestine Tissue
    detail
  • IHC - Anti-MASPIN Picoband Antibody ABO12047
    Anti- MASPIN Picoband antibody, ABO12047, IHC(P)IHC(P): Human Mammary Cancer Tissue
    detail
  • ICC - Anti-MASPIN Picoband Antibody ABO12047
    Anti- MASPIN Picoband antibody, ABO12047, ICCICC: MCF-7 Cell
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession P36952
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Serpin B5(SERPINB5) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 5268
Other Names Serpin B5, Maspin, Peptidase inhibitor 5, PI-5, SERPINB5, PI5
Calculated MW 42100 MW KDa
Application Details Immunocytochemistry , 0.5-1 µg/ml, Human, -
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5 µg/ml, Human, Mouse, Rat
Subcellular Localization Secreted, extracellular space.
Tissue Specificity Normal mammary epithelial cells.
Protein Name Serpin B5
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E.coli-derived human MASPIN recombinant protein (Position: M1-A350). Human MASPIN shares 88% and 89% amino acid (aa) sequence identity with mouse and rat MASPIN, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins.
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the serpin family. Ov-serpin subfamily.
Protein Information
Name SERPINB5
Synonyms PI5
Function Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Cellular Location Secreted, extracellular space.
Tissue Location Normal mammary epithelial cells.
Research Areas
Citations (0)
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Background

SERPINB5 is also known as PI5 or maspin. Maspin (mammary serine protease inhibitor) is a protein that in humans is encoded by the SERPINB5 gene. Maspin is expressed in the skin, prostate, testis, intestine, tongue, lung, and the thymus. Maspin is a member of the serpin superfamily of serine protease inhibitors.[1] The primary function of most members of this family is to regulate the breakdown of proteins by inhibiting the catalytic activity of proteinases. Through this mechanism of action, serpins regulate a number of cellular processes includingphagocytosis, coagulation, and fibrinolysis.

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$ 370.00
Cat# ABO12047
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