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Anti-P2X5 Picoband Antibody

     
  • WB - Anti-P2X5 Picoband Antibody ABO11996
    Anti- P2X5 Picoband antibody, ABO11996, Western blottingAll lanes: Anti P2X5 (ABO11996) at 0.5ug/mlWB: Rat Brain Tissue Lysate at 50ugPredicted bind size: 47KDObserved bind size: 47KD
    detail
  • IHC - Anti-P2X5 Picoband Antibody ABO11996
    Anti- P2X5 Picoband antibody, ABO11996, IHC(P)IHC(P): Mouse Brain Tissue
    detail
  • IHC - Anti-P2X5 Picoband Antibody ABO11996
    Anti- P2X5 Picoband antibody, ABO11996, IHC(P)IHC(P): Rat Brain Tissue
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q93086
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for P2X purinoceptor 5(P2RX5) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 5026
Other Names P2X purinoceptor 5, P2X5, ATP receptor, Purinergic receptor, P2RX5, P2X5
Calculated MW 47205 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Mouse, Rat, Human, By Heat
Western blot, 0.1-0.5 µg/ml, Rat, Human
Subcellular Localization Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed at high levels in brain and immune system.
Protein Name P2X purinoceptor 5
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E.coli-derived human P2X5 recombinant protein (Position: D333-T422). Human P2X5 shares 42% amino acid (aa) sequence identity with rat P2X5.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the P2X receptor family.
Protein Information
Name P2RX5 (HGNC:8536)
Function [Isoform 6]: ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:12761352). Unlike, other P2RX receptors, the P2X5 receptor is also permeable to chloride (PubMed:12761352). May play a supporting role in the inflammatory response (By similarity).
Cellular Location [Isoform 6]: Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P56373}. Note=The absence of the exon 10-encoded amino acids substantially results in subunit aggregation and retention in the cell cytoplasm
Tissue Location Expressed at high levels in brain and immune system
Research Areas
Citations (0)
citation

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Background

P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene. The product of this gene belongs to the family of purinoceptors for ATP. It has been identified that the P2RX5 gene within a BAC contig covering chromosome 17p13. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Quantitative dot blots revealed that P2X5R expression is highest in brain and immune system and is developmentally regulated.

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$ 370.00
Cat# ABO11996
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