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Anti-CNTF Picoband Antibody

     
  • IHC - Anti-CNTF Picoband Antibody ABO11737
    Anti-CNTF Picoband antibody, ABO11737-1.JPGIHC(P): Rat Brain Tissue
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  • IHC - Anti-CNTF Picoband Antibody ABO11737
    Anti-CNTF Picoband antibody, ABO11737-2.JPGIHC(P): Human Intestinal Cancer Tissue
    detail
  • IHC - Anti-CNTF Picoband Antibody ABO11737
    Anti-CNTF Picoband antibody, ABO11737-3.JPGIHC(P): Human Lung Cancer Tissue
    detail
  • WB - Anti-CNTF Picoband Antibody ABO11737
    Anti-CNTF Picoband antibody, ABO11737-4.jpgAll lanes: Anti-CNTF(ABO11737) at 0.5ug/mlWB: Recombinant Human CNTF Protein 0.5ngPredicted bind size: 28KDObserved bind size: 28KD
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P26441
Host Rabbit
Reactivity Human, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Ciliary neurotrophic factor(CNTF) detection. Tested with WB, IHC-P in Human;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 1270
Other Names Ciliary neurotrophic factor, CNTF, CNTF
Calculated MW 22931 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Rat, By Heat
Western blot, 0.1-0.5 µg/ml, Human
Subcellular Localization Cytoplasm.
Tissue Specificity Nervous system.
Protein Name Ciliary neurotrophic factor
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E.coli-derived human CNTF recombinant protein (Position: A2-M200). Human CNTF shares 83% and 84% amino acid (aa) sequences identity with mouse and rat CNTF, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the CNTF family.
Protein Information
Name CNTF
Function CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Cellular Location Cytoplasm.
Tissue Location Nervous system.
Research Areas
Citations (0)
citation

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Background

Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The CNTF gene is located on chromosome 11, as determined using human-hamster somatic cell hybrids. The CNTF protein is highly conserved in evolution. The amino acid (aa) sequences of rat and rabbit CNTF translated from cDNAs display approx. 85% homology with the deduced aa sequence encoding human CNTF. CNTF induces weight loss and improves glucose tolerance in humans and rodents. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.

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$ 370.00
Cat# ABO11737
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