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Anti-TREX2 Picoband Antibody

     
  • WB - Anti-TREX2 Picoband Antibody ABO11723
    Western blot analysis of TREX2 expression in HELA whole cell lysates (lane 1) and MCF-7 whole cell lysates (lane 2). TREX2 at 37KD was detected using rabbit anti- TREX2 Antigen Affinity purified polyclonal antibody (Catalog # ABO11723) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method .
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9BQ50
Host Rabbit
Reactivity Human
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Three prime repair exonuclease 2(TREX2) detection. Tested with WB in Human.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 11219
Other Names Three prime repair exonuclease 2, 3.1.11.2, 3'-5' exonuclease TREX2, TREX2
Calculated MW 30621 MW KDa
Application Details Western blot, 0.1-0.5 µg/ml, Human
Subcellular Localization Nucleus .
Tissue Specificity Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus. .
Protein Name Three prime repair exonuclease 2
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E. coli-derived human TREX2 recombinant protein (Position: E69-A279). Human TREX2 shares 88.6% amino acid (aa) sequence identity with mouse TREX2.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins.
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name TREX2
Function Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
Cellular Location Nucleus.
Tissue Location Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.
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Background

Three prime repair exonuclease 2 is an enzyme that in humans is encoded by the TREX2 gene. By genomic sequence analysis, the TREX2 gene is mapped to chromosome Xq28. This gene encodes a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

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$ 370.00
Cat# ABO11723
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