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> home > Products > Primary Antibodies > Antibody Collections > Immunity > Anti-CD25/IL-2sR alpha Antibody
Anti-CD25/IL-2sR alpha Antibody
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P01589 |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit alpha(IL2RA) detection. Tested with WB, IHC-P in Human. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 3559 |
|---|---|
| Other Names | Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25, IL2RA |
| Calculated MW | characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression KDa |
| Application Details | Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, By Heat Western blot, 0.1-0.5 µg/ml, Human |
| Subcellular Localization | sc 13946|sc 19628|sc 365511|sc 365912|sc 374034|sc 393326|sc 57297|sc 664|sc 665|sc 666 |
| Tissue Specificity | |immunology|adaptive immunity|t cells| immunology|innate immunity|cytokines|interleukins |
| Source | Interleukin-2 receptor subunit alpha;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;CD25;IL2RA; |
| Protein Name | Interleukin-2 receptor subunit alpha |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CD25/IL-2sR Alpha (39-57aa MAYKEGTMLNCECKRGFRR). |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Receptor for interleukin-2. |
| Name | IL2RA |
|---|---|
| Function | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
IL2RA(Interleukin 2 receptor, alpha), also called IL2R, IL2R, Alpha Chain or CD25, is a protein that in humans is encoded by the IL2RA gene.The IL2RA gene is mapped on 10p15.1. IL2RA is composed of strand-swapped sushi-like" domains
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$ 370.00
Cat# ABO11056
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