Anti-Beta-HCG Antibody (Monoclonal, PC-2)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P01233 |
Host | Mouse |
Isotype | Mouse IgG1 |
Reactivity | Human |
Clonality | Monoclonal |
Format | Lyophilized |
Description | Mouse IgG monoclonal antibody for beta-HCG, chorionic gonadotropin, beta polypeptide (CGB) detection. Tested with IHC-P in Human. Cross-reactivities with LH, FSH and TSH are less than 0.3%. |
Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Calculated MW | 17739 MW KDa |
---|---|
Application Details | Immunohistochemistry(Paraffin-embedded Section), 2 µg/ml, Human, By Heat |
Subcellular Localization | Secreted. |
Tissue Specificity | Placenta. |
Protein Name | Choriogonadotropin subunit beta |
Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
Clone Names | PC-2 |
Immunogen | Purified human Chorionic Gonadotropin. |
Purification | Ascites |
Cross Reactivity | Cross-reactivities with LH, FSH and TSH are less than 0.3%. |
Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
Sequence Similarities | Belongs to the glycoprotein hormones subunit beta family. |
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Provided below are standard protocols that you may find useful for product applications.
Background
beta-HCG(beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain(CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.
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