Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.Interactive mTOR Signaling Pathway
Click on any interested protein or antibody ID in the mTOR Signaling pathway to list relevant products below.The mammalian target of rapamycin (mTOR) signaling pathway integrates intracellular and extracellular signals to regulate cell metabolism, growth, proliferation and survival. This pathway is activated during a range of cellular processes (tumor formation, angiogenesis, insulin resistance, adipogenesis, T-lymphocyte activation, etc.) and is dysregulated in diseases such as cancer and diabetes. mTOR inhibitors such as rapamycin and its analogues are used in treatment of solid tumors, organ transplantation, circulatory disease and rheumatoid arthritis.
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