Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.Interactive Apoptosis Pathway
Click on any interested protein or antibody ID in the Apoptosis pathway to reveal the list of the products below.Apoptosis (programmed cell death) is characterized by cell shrinkage, membrane blebbing, phagocytic engulfment of the fragmented cell, DNA fragmentation and mitochondrial release of cytochrome C. Tightly regulated termination is essential to cull unneeded, aging, mutated, or infected cells. Dysregulation of death/survival signals in the apoptotic pathway is implicated in a broad range of human diseases. Controlling fidelity of the apoptotic pathways may lead to new methods to treat challenging diseases.
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